Sandalwood

Sandalwood has been used in connection with the following conditions (refer to the individual health concern for complete information):

Rating	Health Concerns
	Infection
Reliable and relatively consistent scientific data showing a substantial health benefit. Contradictory, insufficient, or preliminary studies suggesting a health benefit or minimal health benefit. An herb is primarily supported by traditional use, or the herb or supplement has little scientific support and/or minimal health benefit.

Historical or traditional use (may or may not be supported by scientific studies): Sandalwood oil was used traditionally by herbalists to treat skin diseases, acne, dysentery, gonorrhea, and a number of other conditions.¹ In Traditional Chinese Medicine, sandalwood oil is considered an excellent sedating agent.

Active constituents: The volatile oil contains high amounts of alpha- and beta-santalol. According to a test tube study, these small molecules possess antibacterial properties.² This makes it a potential topical treatment for skin infections. Synthetic sandalwood oil does not contain these active ingredients. Internal use of sandalwood is approved by the German Commission E for the supportive treatment of infections of the lower urinary tract (usually the urinary bladder).³ However, clinical trials are lacking to support this use.

How much is usually taken? The German Commission E monograph suggests 1/4 teaspoon (1–1.5 grams) of the volatile oil for the supportive treatment of urinary tract infections.⁴ This should only be done under the supervision of a doctor. Treatment should not exceed six weeks. For external use, a few drops of sandalwood oil are dissolved in 6 ounces (180 ml) of water and applied directly to the infected area of skin several times daily.

Are there any side effects or interactions? Some people may experience mild skin irritation from topical application of sandalwood oil.⁵ People with kidney disease should not use sandalwood internally. Until more is known, sandalwood oil should be avoided for internal use during pregnancy and breast-feeding. Infants and children should not take sandalwood oil internally.

At the time of writing, there were no well-known drug interactions with sandalwood.

References:

1. Duke JA. CRC Handbook of Medicinal Herbs. Boca Raton, FL: CRC Press, 1985, 426–7.

2. Okazai K, Oshima S. Antibacterial activity of higher plants. XXIV. Antimicrobial effect of essential oils (5). J Pharm Soc Japan 1953;73:344–7.

3. Blumenthal M, Busse WR, Goldberg A, et al. (eds). The Complete Commission E Monographs: Therapeutic Guide to Herbal Medicines. Boston, MA: Integrative Medicine Communications, 1998, 199.

4. Blumenthal M, Busse WR, Goldberg A, et al. (eds). The Complete Commission E Monographs: Therapeutic Guide to Herbal Medicines. Boston, MA: Integrative Medicine Communications, 1998, 199.

5. Blumenthal M, Busse WR, Goldberg A, et al. (eds). The Complete Commission E Monographs: Therapeutic Guide to Herbal Medicines. Boston, MA: Integrative Medicine Communications, 1998, 199.

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The information presented in Healthnotes is for informational purposes only. It is based on scientific studies (human, animal, or in vitro), clinical experience, or traditional usage as cited in each article. The results reported may not necessarily occur in all individuals. For many of the conditions discussed, treatment with prescription or over-the-counter medication is also available. Consult your doctor, practitioner, and/or pharmacist for any health problem and before using any supplements or before making any changes in prescribed medications. Information expires December 2003.