Are there any side effects or interactions? Coltsfoot contains
potentially liver-damaging pyrrolizidine alkaloids, with much higher levels appearing in the
root than in the leaves or the flowers. Animal studies using amounts of coltsfoot hundreds of
times higher than those used as medicine have shown these alkaloids can cause cancer in
animals.8 A single case of an infant who developed liver disease and died after the
mother drank tea containing coltsfoot during pregnancy has been reported.9 This
eventually led to the banning of coltsfoot in Germany in 1992.
Coltsfoot should not be taken during pregnancy or
breast-feeding.10 Otherwise, coltsfoot is generally safe.11
Coltsfoot should be differentiated from the plant called western coltsfoot (Petastites
frigidus), because western coltsfoot can contain higher amounts of pyrrolizidine
alkaloids. Use of western coltsfoot is not recommended.
At the time of writing, there were no well-known drug interactions
with coltsfoot.
References:
1. Weiss RF. Herbal Medicine. Gothenburg, Sweden: Ab Arcanum and
Beaconsfield, UK: Beaconsfield Publishers Ltd, 1988, 196–7.
2. Blumenthal M, Busse WR, Goldberg A, et al. (eds). The Complete
German Commission E Monographs: Therapeutic Guide to Herbal Medicines. Austin: American
Botanical Council and Boston: Integrative Medicine Communications, 1998, 114–5.
3. Foster S. Herbal Renaissance. Salt Lake City: Gibbs-Smith
Publisher, 1993, 74–8.
4. Weiss RF. Herbal Medicine. Gothenburg, Sweden: Ab Arcanum and
Beaconsfield, UK: Beaconsfield Publishers Ltd., 1988, 196–7.
5. Gruenwald J, Brendler T, Jaenicke C (eds). PDR for Herbal
Medicines. Montvale, NJ: Medical Economics Company, 1998, 1993–5.
6. Weiss RF. Herbal Medicine. Gothenburg, Sweden: Ab Arcanum and
Beaconsfield, UK: Beaconsfield Publishers Ltd., 1988, 196–7.
7. Weiss RF. Herbal Medicine. Gothenburg, Sweden: Ab Arcanum and
Beaconsfield, UK: Beaconsfield Publishers Ltd., 1988, 196–7.
8. Weiss RF. Herbal Medicine. Gothenburg, Sweden: Ab Arcanum and
Beaconsfield, UK: Beaconsfield Publishers Ltd., 1988, 196–7.
9. Roulet M, Laurini R, Rivier L, Calame A. Hepatic veno-occlusive
disease in newborn infant of a woman drinking herbal tea. J Pediatrics
1988;112:433–6.
10. McGuffin M, Hobbs C, Upton R, Goldberg A. American Herbal
Products Association’s Botanical Safety Handbook. Boca Raton, FL: CRC Press, 1997,
117–8.
11. Weiss RF. Herbal Medicine. Gothenburg, Sweden: Ab Arcanum
and Beaconsfield, UK: Beaconsfield Publishers Ltd., 1988, 196–7.
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purposes only. It is based on scientific studies (human, animal, or in vitro),
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before making any changes in prescribed medications. Information expires December 2003.