Zolmitriptan

Also indexed as: Zomig®

Zolmitriptan is used to treat acute attacks of migraine headache and is in a class of drugs known as serotonin antagonists. There are currently no reported nutrient or herb interactions involving zolmitriptan.

Summary of Interactions with Vitamins, Herbs, and Foods
(for details about the summarized interactions, read the full article)

Avoid Avoid: Adverse interaction—Avoid these supplements when taking this medication because taking them together may cause undesirable or dangerous results.

5-Hydroxytryptophan (5-HTP)*

L-tryptophan*

Depletion or interference

None known

Side effect reduction/prevention

None known

Supportive interaction

None known

Reduced drug absorption/bioavailability

None known

An asterisk (*) next to an item in the summary indicates that the interaction is supported only by weak, fragmentary, and/or contradictory scientific evidence.

Interactions with Dietary Supplements

5-Hydroxytryptophan (5-HTP)
Zolmitriptan works by stimulating serotonin receptors in the brain. 5-HTP and L-tryptophan are converted to serotonin in the brain, and taking them with zolmitriptan could increase zolmitriptan-induced side effects. However, no interactions have yet been reported with zolmitriptan and 5-HTP or L-tryptophan.