Active constituents: The glycoside salicin, from which the
body can split off salicylic acid, is thought to be the source of the anti-inflammatory and
pain-relieving actions of willow.3 The analgesic actions of willow are typically
slow to develop but may last longer than the effects of standard aspirin products. One trial
has found that a combination herbal product including 100 mg willow bark taken for two months
improved functioning via pain relief in people with
osteoarthritis.4 Another trial found that 1360 mg of willow bark extract per
day (delivering 240 mg of salicin) for two weeks was somewhat effective in treating pain
associated with knee and/or hip
osteoarthritis.5 Use of high amounts of willow bark extract may also help
people with low back pain. One four-week trial found 240 mg of salicin from a willow extract
was effective in reducing exacerbations of low back pain.6
How much is usually taken? Willow extracts standardized for salicin content are
available. The commonly recommended intake of salicin has been 60–120 mg per
day.7 However, newer studies suggest a higher salicin intake of 240 mg per day may
be more effective for treating pain.8 A willow tea can be prepared from
1/4–1/2 teaspoon (1–2 grams) of bark boiled in about 7 ounces (200 ml) of water
for ten minutes. Five or more cups (1250 ml) of this tea can be drunk per day. Tincture,
1–1 1/2 teaspoons (5–8 ml) three times per day, is also occasionally used.
Are there any side effects or interactions? As with aspirin,
some people may experience stomach upset from taking willow. Although such symptoms are less
likely from willow than from aspirin, people with ulcers and gastritis
should, nevertheless, avoid this herb.9 Again, as with aspirin, willow should not
be used to treat fevers in children since it may cause Reye’s syndrome.
Are there any drug interactions? Certain medications may
interact with willow. Refer to the drug interactions
safety check for a list of those medications.
References:
1. Weiss RF. Herbal Medicine. Gothenburg, Sweden: Ab Arcanum,
1988, 31, 303.
2. Foster S. 101 Medicinal Herbs. Loveland, CO: Interweave
Press, 1998, 210–1.
3. Bradley PR (ed). British Herbal Compendium, vol 1.
Bournemouth, Dorset, UK: British Herbal Medicine Association, 1992, 224–6.
4. Mills SY, Jacoby RK, Chacksfield M, Willoughby M. Effect of a
proprietary herbal medicine on the relief of chronic arthritic pain: A double-blind study.
Br J Rheum 1996;35:874–8.
5. Schmid B, Tschirdewahn B, Kàtter I, et al. Analgesic effects of
willow bark extract in osteoarthritis: results of a clinical double-blind trial. Fact
1998;3:186.
6. Chrubasik S, Eisenberg E, Balan E, et al. Treatment of low back pain
exacerbations with willow bark extract: A randomized double-blind study. Am J Med
2000;109:9–14.
7. Blumenthal M, Busse WR, Goldberg A, et al. (eds). The Complete
Commission E Monographs: Therapeutic Guide to Herbal Medicines. Boston, MA: Integrative
Medicine Communications, 1998, 230.
8. Chrubasik S, Eisenberg E, Balan E, et al. Treatment of low back pain
exacerbations with willow bark extract: A randomized double-blind study. Am J Med
2000;109:9–14.
9. Blumenthal M, Busse WR, Goldberg A, et al. (eds). The Complete
Commission E Monographs: Therapeutic Guide to Herbal Medicines. Boston, MA: Integrative
Medicine Communications, 1998, 230.
Copyright © 2002 Healthnotes, Inc. All rights reserved.
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The information presented in Healthnotes is for informational
purposes only. It is based on scientific studies (human, animal, or in vitro),
clinical experience, or traditional usage as cited in each article. The results reported may
not necessarily occur in all individuals. For many of the conditions discussed, treatment with
prescription or over-the-counter medication is also available. Consult your doctor,
practitioner, and/or pharmacist for any health problem and before using any supplements or
before making any changes in prescribed medications. Information expires December 2003.