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Photo copyright Steven Foster
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Common name: Salai guggal
Botanical name: Boswellia serrata
Parts used and where grown: Boswellia is a moderate to large
branching tree found in the dry hilly areas of India. When the tree trunk is tapped, a gummy
oleoresin is exuded. A purified extract of this resin is used in modern herbal
preparations.
Boswellia has been used in
connection with the following conditions (refer to the individual
health concern for complete information):
Historical or traditional use (may or may not
be supported by scientific studies): In the ancient Ayurvedic medical texts of
India, the gummy exudate from boswellia is grouped with other gum resins and referred to
collectively as guggals. Historically, the guggals were recommended by Ayurvedic physicians for a variety of conditions,
including osteoarthritis, rheumatoid arthritis, diarrhea, dysentery, pulmonary disease, and ringworm.
Active constituents: The gum oleoresin consists of essential
oils, gum, and terpenoids. The terpenoid portion contains the boswellic acids that have been
shown to be the active constituents in boswellia.1 Today, extracts are typically
standardized to contain 37.5–65% boswellic acids.
Studies have shown that boswellic acids have an anti-inflammatory action2
—much like the conventional nonsteroidal anti-inflammatory drugs (NSAIDs) used for inflammatory conditions. Boswellia inhibits
pro-inflammatory mediators in the body, such as leukotrienes.3 As opposed to
NSAIDs, long-term use of boswellia does not appear to cause irritation or ulceration of the
stomach. One small, controlled, double-blind trial has shown that boswellia extract may be
helpful for ulcerative
colitis.4
How much is usually taken? The standardized extract of the gum
oleoresin of boswellia is recommended by many doctors. For rheumatoid arthritis or osteoarthritis, 150 mg of boswellic acids are taken three
times per day.5 As an example, if an extract contains 37.5% boswellic acids, 400 mg
of the extract would be taken three times daily. Treatment with boswellia generally lasts
eight to twelve weeks. In the one clinical trial to date, people with ulcerative colitis used 550 mg of boswellia extract
three times per day.
Are there any side effects or interactions? Boswellia is
generally safe when used as directed. Rare side effects can include diarrhea, skin rash, and nausea. Any inflammatory joint
condition should be closely monitored by a physician.
At the time of writing, there were no well-known drug interactions
with boswellia.
References:
1. Safayhi H, Sailer ER, Amnon HPT. 5-lipoxygenase inhibition by
acetyl-11-keto-b-boswellic acid. Phytomed 1996;3:71–2.
2. Safayhi H, Mack T, Saieraj J, et al. Boswellic acids: Novel, specific,
nonredox inhibitors of 5-lipoxygenase. J Pharmacol Exp Ther
1992;261:1143–6.
3. Singh GB, Atal CK. Pharmacology of an extract of salai guggal
ex-Boswellia serrata, a new non-steroidal anti-inflammatory agent. Agents
Actions 1986;18:407–12.
4. Gupta I, Parihar A, Malhotra P, et al. Effects of Boswellia
serrata gum resin in patients with ulcerative colitis. Eur J Med Res
1997;2:37–43.
5. Etzel R. Special extract of Boswellia serrata (H15) in the treatment
of rheumatoid arthritis. Phytomed 1996;3:91–4.
Copyright © 2002 Healthnotes, Inc. All rights reserved.
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The information presented in Healthnotes is for informational
purposes only. It is based on scientific studies (human, animal, or in vitro),
clinical experience, or traditional usage as cited in each article. The results reported may
not necessarily occur in all individuals. For many of the conditions discussed, treatment with
prescription or over-the-counter medication is also available. Consult your doctor,
practitioner, and/or pharmacist for any health problem and before using any supplements or
before making any changes in prescribed medications. Information expires December 2003.
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