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Photo copyright Steven Foster
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Botanical name: Momordica charantia
Parts used and where grown: Bitter melon grows in tropical
areas, including parts of East Africa, Asia, the Caribbean, and South America, where it is
used as a food as well as a medicine. The fruit of this plant lives up to its name—it
tastes bitter. Although the seeds, leaves, and vines of bitter melon have all been used, the
fruit is the safest and most prevalent part of the plant used medicinally.
Bitter melon has been used
in connection with the following conditions (refer to the individual
health concern for complete information):
Historical or traditional use (may or may not
be supported by scientific studies): Being a relatively common food item, bitter
melon was traditionally used for an array of conditions by people in tropical regions.
Numerous infections, cancer, and diabetes
were among the most common conditions it has been purported to improve.1 The leaves
and fruit have both been used in the Western world to make teas and beer or to season
soups.
Active constituents: At least three different groups of
constituents in bitter melon have been reported to have blood-sugar lowering actions of
potential benefit in diabetes mellitus. These include a
mixture of steroidal saponins known as charantin, insulin-like peptides, and alkaloids. It is
still unclear which of these is most effective, or if all three work together. Some clinical
trials have confirmed the benefit of bitter melon for people with diabetes.2
In traditional herbal medicine, bitter melon—like other bitter-tasting herbs—is
thought to stimulate digestive function and improve appetite. This has yet to be tested in
human studies.
How much is usually taken? For those with a taste or tolerance
for bitter flavor, a small melon can be eaten as food, or up to 3 1/3 ounces (100 ml) of a
decoction or 2 ounces (60 ml) of fresh juice can be drunk per day.3 Though still
bitter, tinctures of bitter melon (1 teaspoon [5 ml] two to three times per day) are also
sometimes used. The amounts recommended would be appropriate for people with diabetes.
Are there any side effects or interactions? Ingestion of
excessive amounts of bitter melon juice (several times more than the amount recommended above)
can cause abdominal pain and diarrhea.4
Excessive ingestion of the seeds had been associated with headache, fever, and coma. Bitter
melon is not recommended for pregnant women. People
with hypoglycemia (low blood sugar) should not take
bitter melon, because it may trigger or worsen the problem. This effect has been reported in
two young children and one adult patient with
diabetes.
At the time of writing, there were no well-known drug interactions
with bitter melon.
References:
1. Duke JA. CRC Handbook of Medicinal Herbs. Boca Raton, FL: CRC
Press, 1985, 315–6.
2. Raman A, Lau C. Anti-diabetic properties and phytochemistry of
Momordica charantia L (Curcurbitaceae). Phytomed 1996;2:349–62.
3. Werbach MR, Murray MT. Botanical Influences on Illness.
Tarzana, CA: Third Line Press, 1994, 139–41.
4. Brown DJ, Gaby A, Reichert R, Yarnell E. Phytotherapeutic and
nutritional approaches to diabetes mellitus. Quart Rev Nat Med
1998;Winter:329–54.
Copyright © 2002 Healthnotes, Inc. All rights reserved.
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The information presented in Healthnotes is for informational
purposes only. It is based on scientific studies (human, animal, or in vitro),
clinical experience, or traditional usage as cited in each article. The results reported may
not necessarily occur in all individuals. For many of the conditions discussed, treatment with
prescription or over-the-counter medication is also available. Consult your doctor,
practitioner, and/or pharmacist for any health problem and before using any supplements or
before making any changes in prescribed medications. Information expires December 2003.
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