Also indexed as: Pentoxil®, Trental®
Pentoxifylline decreases blood thickness and improves red blood cell flexibility.
Pentoxifylline is used to improve symptoms of intermittent claudication and in the treatment
of other circulatory disorders.
Safetychecker Summary
for Pentoxifylline
(for details about the summarized interactions, read the full article)
 May be Beneficial: Supportive
interaction—Taking these supplements may support or otherwise help your medication
work better. |
Vitamin E
|
| Depletion or interference |
None known
|
| Side effect reduction/prevention |
None known
|
| Reduced drug
absorption/bioavailability |
None known
|
| Adverse interaction |
None known
|
An asterisk (*) next to an item in the summary indicates that the
interaction is supported only by weak, fragmentary, and/or contradictory scientific
evidence.
Interactions with Dietary Supplements
Vitamin E
The combination of vitamin E and pentoxifylline has been used successfully to reduce damage to
normal tissues caused by radiation therapy.1
Interactions with Foods and Other Compounds
Food
Pentoxifylline should be taken with meals.2
References:
1. Delanian S, Balla-Mekias S, Lefaix JL. Striking regression of chronic
radiotherapy damage in a clinical trial of combined pentoxifylline and tocopherol. J Clin
Oncol 1999;17:3283–90.
2. Threlkeld DS, ed. Blood Modifiers, Hemorheologic Agent,
Pentoxifylline. In Facts and Comparisons Drug Information. St. Louis, MO: Facts and
Comparisons, Mar 1997, 89f–9g.
Copyright © 2002 Healthnotes, Inc. All rights
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Safetychecker.
The information presented in Healthnotes is for informational
purposes only. It is based on scientific studies (human, animal, or in vitro),
clinical experience, or traditional usage as cited in each article. The results reported may
not necessarily occur in all individuals. For many of the conditions discussed, treatment with
prescription or over-the-counter medication is also available. Consult your doctor,
practitioner, and/or pharmacist for any health problem and before using any supplements or
before making any changes in prescribed medications. Information expires December 2003.
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