Also indexed as: Claritin®
Loratadine is a selective antihistamine used to relieve
allergic rhinitis (seasonal allergy) symptoms, including sneezing, runny nose, itching,
and watery eyes. It is also used to treat people with idiopathic urticaria. Loratadine is
available alone and in a combination product.
Safetychecker Summary
for Loratadine
(for details about the summarized interactions, read the full article)
| Depletion or interference |
None known
|
| Side effect reduction/prevention |
None known
|
| Supportive interaction |
None known
|
| Reduced drug
absorption/bioavailability |
None known
|
| Adverse interaction |
None known
|
An asterisk (*) next to an item in the summary indicates that the
interaction is supported only by weak, fragmentary, and/or contradictory scientific
evidence.
Interactions with Foods and Other Compounds
Food
Food slows the absorption of loratadine and also increases the total amount of the drug
absorbed.1 It is recommended that loratadine be taken on an empty
stomach.2
Alcohol
Selective antihistamines, including loratadine, may cause drowsiness or dizziness, although it
is less likely than with nonselective antihistamines.3 Alcohol can intensify
drowsiness and dizziness, increasing the risk of accidental injury. People taking loratadine
should use alcohol only with caution.
References:
1. Threlkeld DS, ed. Respiratory Drugs, Antihistamines. In Facts and
Comparisons Drug Information. St. Louis, MO: Facts and Comparisons, May 1998, 194b.
2. Threlkeld DS, ed. Respiratory Drugs, Antihistamines. In Facts and
Comparisons Drug Information. St. Louis, MO: Facts and Comparisons, May 1998, 194b.
3. Threlkeld DS, ed. Respiratory Drugs, Antihistamines. In Facts and
Comparisons Drug Information. St. Louis, MO: Facts and Comparisons, May 1998, 194b.
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purposes only. It is based on scientific studies (human, animal, or in vitro),
clinical experience, or traditional usage as cited in each article. The results reported may
not necessarily occur in all individuals. For many of the conditions discussed, treatment with
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before making any changes in prescribed medications. Information expires December 2003.
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