Also indexed as: 3TC, Epivir®
Lamivudine is used to treat human immunodeficiency virus (HIV) infection and is in a class of drugs known as
antivirals.
Safetychecker Summary
for Lamivudine
(for details about the summarized interactions, read the full article)
 May be Beneficial: Supportive
interaction—Taking these supplements may support or otherwise help your medication
work better. |
Sho-saiko-to*
|
| Depletion or interference |
None known
|
| Side effect reduction/prevention |
None known
|
| Reduced drug
absorption/bioavailability |
None known
|
| Adverse interaction |
None known
|
An asterisk (*) next to an item in the summary indicates that the
interaction is supported only by weak, fragmentary, and/or contradictory scientific
evidence.
Interactions with Herbs
Sho-saiko-to
Test tube studies show that the herbal combination sho-saiko-to enhances the antiviral
activity of lamivudine.1 Sho-saiko-to contains extracts of seven herbs, including
Bupleuri radix, Pinelliae tuber, Scutellariae radix, Zizyphi fructus, ginseng
(Ginseng radix), licorice (Glycyrrhizae
radix), and ginger (Zingibers rhizoma).
Controlled studies are needed to determine whether taking sho-saiko-to might enhance the
beneficial effects of lamivudine.
References:
1. Piras G, Makino M, Baba M. Sho-saiko-to, a traditional kampo medicine,
enhances the anti-HIV-1 activity of lamivudine (3TC) in vitro. Microbiol Immunol
1997;41:835–9.
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clinical experience, or traditional usage as cited in each article. The results reported may
not necessarily occur in all individuals. For many of the conditions discussed, treatment with
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before making any changes in prescribed medications. Information expires December 2003.
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