Atropine

Atropine is an alkaloid (a family of chemicals with pharmacologic activity and a common structure) that affects the nervous system. It is found in deadly nightshade (Atropa belladonna) and other plants. Some effects of atropine include blurred vision, dilated pupils, constipation, dry mouth, and dry eyes.

Atropine is available as a prescription drug, synthesized in the laboratory. It is used to help restore or control heart function. It is used in combination with other drugs to treat other health problems including diarrhea and excessive salivation (saliva production). Atropine drops (Isopto® Atropine and others) are used to dilate pupils for eye exams.

Safetychecker Summary for Atropine
(for details about the summarized interactions, read the full article)

Avoid Avoid: Reduced drug absorption/bioavailability—Avoid these supplements when taking this medication since the supplement may decrease the absorption and/or activity of the medication in the body.

Tannin-containing herbs* such as green tea, black tea, uva ursi, black walnut, red raspberry, oak, and witch hazel
Depletion or interference

None known
Side effect reduction/prevention

None known
Supportive interaction

None known
Adverse interaction

None known

An asterisk (*) next to an item in the summary indicates that the interaction is supported only by weak, fragmentary, and/or contradictory scientific evidence.

Interactions with Herbs

Tannin-containing herbs
Tannins are a group of unrelated chemicals that give plants an astringent taste. Herbs containing high amounts of tannins, such as green tea (Camellia sinensis), black tea, uva ursi (Arctostaphylos uva-ursi), black walnut (Juglans nigra), red raspberry (Rubus idaeus), oak (Quercus spp.), and witch hazel (Hamamelis virginiana), may interfere with the absorption of atropine taken by mouth.1

References:

1. Brinker F. Herb Contraindications and Drug Interactions. Sandy, OR: Eclectic Institute, 1997, 100.