Amphotericin B

Also indexed as: Fungizone®

Amphotericin B is an antifungal drug. Topically, it is used to treat skin yeast infections. Intravenously, it is used to treat a variety of life-threatening fungal infections.

Safetychecker Summary for Amphotericin B
(for details about the summarized interactions, read the full article)

Beneficial May be Beneficial: Depletion or interference—The medication may deplete or interfere with the absorption or function of the nutrient. Taking these nutrients may help replenish them.

Magnesium*

Side effect reduction/prevention

None known

Supportive interaction

None known

Reduced drug absorption/bioavailability

None known

Adverse interaction

None known

An asterisk (*) next to an item in the summary indicates that the interaction is supported only by weak, fragmentary, and/or contradictory scientific evidence.

Interactions with Dietary Supplements

Magnesium
Amphotericin B has been reported to increase urinary excretion of magnesium.1 It remains unclear whether it is important for people taking this drug to supplement magnesium.

References:

1. McLean R. Magnesium and its therapeutic uses: A review. Am J Med 1994;96: 63–76.